rheumatoid factors in primary and reactive macroglobulinaemia.
نویسندگان
چکیده
منابع مشابه
rheumatoid factors in primary and reactive macroglobulinaemia.
The occurrence of 1gM (= /32m)-globulins capable of reacting with IgG (= 7S-y)-globulin, the socalled rheumatoid factors, is not restricted to rheumatoid arthritis, but has been reported in a variety of conditions unrelated to the collagen diseases. The importance of these "false positive" reactions lies in the possibility of obtaining more information about the origin of the rheumatoid factors...
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15 صفحه اولSeronegative rheumatoid arthritis, rheumatoid factor cross reactive idiotype expression, and hidden rheumatoid factors.
The major rheumatoid factor cross reactive idiotype (RCRI), defined by prototypic monoclonal rheumatoid factors (RFs), is expressed as a dominant idiotype by pokeweed mitogen induced plasma cells obtained from seropositive (RF+) patients with rheumatoid arthritis (RA). Some patients who meet clinical diagnostic criteria for RA set by the American Rheumatism Association fail to express RFs at an...
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Differential Expression of Rheumatoid Factor-Associated Cross-Reactive Idiotypes in Iranian Seropositive and Seronegative Patients with Rheumatoid Arthritis
High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1965
ISSN: 0003-4967
DOI: 10.1136/ard.24.5.458